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何凌骁

何凌骁 副教授

职务:

电子邮件:lhe@xmu.edu.cn

办公地点:厦门大学翔安校区bet体育365官网正规曾宪梓楼401室

主要研究领域:健康老龄化,肌少症,衰弱,表观遗传


学习经历

2015.10 – 2019.11 欧盟伊拉斯谟Move-AGE联合博士项目

         鲁汶天主教大学(比利时),生物医学,博士

         曼彻斯特城市大学(英国),运动人体科学,博士

2011.09 – 2014.07 北京体育大学,运动人体科学,硕士

2007.09 – 2011.07 北京体育大学,运动康复与健康,学士

工作经历

2021.11至今 bet体育365官网正规副教授

2019.10 – 2021.09 图卢兹大学中心医院老年医学研究中心(法国)博士后研究员 

主要研究方向

健康老龄化,肌少症,衰弱,表观遗传

文章发表

1.Khanal P, Williams AG, He L, et al. Sarcopenia, Obesity, and Sarcopenic Obesity: Relationship with Skeletal Muscle Phenotypes and Single Nucleotide Polymorphisms. J Clin Med. 2021;10(21):4933. doi:10.3390/jcm10214933.

2.Khanal P, He L, Degens H, et al. Dietary Protein Requirement Threshold and Micronutrients Profile in Healthy Older Women Based on Relative Skeletal Muscle Mass. Nutrients. 2021;13(9):3076. doi:10.3390/nu13093076.

3.Khanal P, He L, Stebbings GK, et al. Static one-leg standing balance test as a screening tool for low muscle mass in healthy elderly women. Aging Clin Exp Res. March 2021. doi:10.1007/s40520-021-01818-x.

4.He L, Morley JE, Aggarwal G, et al. Plasma neurofilament light chain is associated with cognitive decline in non-dementia older adults. Sci Rep. 2021;11(1):13394. doi:10.1038/s41598-021-91038-0.

5.Raffin J, Rolland Y, He L, et al. Cross-sectional and longitudinal interaction effects of physical activity and APOE-ε4 on white matter integrity in older adults: The MAPT study. Maturitas. 2021;152:10-19. doi:10.1016/j.maturitas.2021.06.010.

6.He L, Souto Barreto P, Giudici KV, et al. Five‐Year Lower Extremity Function is Associated with White Matter Abnormality in Older Adults. J Am Geriatr Soc. 2021;69(4):995-1002. doi:10.1111/jgs.16989.

7.Khanal P, He L, Herbert AJ, et al. The Association of Multiple Gene Variants with Ageing Skeletal Muscle Phenotypes in Elderly Women. Genes. 2020;11(12):1459. doi:10.3390/genes11121459.

8.He L, Barreto P de S, Nguyen AD, et al. Combined low plasma Aβ 42/Aβ 40 ratio and high neurofilament light chain levels are associated with both cognitive and physical function declines over time in non‐dementia older adults with memory complaints. Alzheimers Dement. 2020;16(S5). doi:10.1002/alz.047540.

9.He L, de Souto Barreto P, Giudici KV, et al. Cross-Sectional and Longitudinal Associations Between Plasma Neurodegenerative Biomarkers and Physical Performance Among Community-Dwelling Older Adults. Newman AB, ed. J Gerontol Ser A. November 2020:glaa284. doi:10.1093/gerona/glaa284.

10.He L, Khanal P, Morse CI, Williams A, Thomis M. Associations of combined genetic and epigenetic scores with muscle size and muscle strength: a pilot study in older women. J Cachexia Sarcopenia Muscle. 2020;11(6):1548-1561. doi:10.1002/jcsm.12585.

11.He L, de Souto Barreto P, Aggarwal G, et al. Plasma Aβ and neurofilament light chain are associated with cognitive and physical function decline in non-dementia older adults. Alzheimers Res Ther. 2020;12(1):128. doi:10.1186/s13195-020-00697-0.

12.He L, Van Roie E, Bogaerts A, et al. The Genetic Effect on Muscular Changes in an Older Population: A Follow-Up Study after One-Year Cessation of Structured Training. Genes. 2020;11(9):968. doi:10.3390/genes11090968.

13.Khanal P, He L, Stebbings G, et al. Prevalence and association of single nucleotide polymorphisms with sarcopenia in older women depends on definition. Sci Rep. 2020;10(1):2913. doi:10.1038/s41598-020-59722-9.

14.He L, Khanal P, Morse CI, Williams A, Thomis M. Differentially methylated gene patterns between age‐matched sarcopenic and non‐sarcopenic women. J Cachexia Sarcopenia Muscle. 2019;10(6):1295-1306. doi:10.1002/jcsm.12478.

15.He L, Zhang X, Lv Y, Gu B, Zhao L. Effects of 8 weeks of moderate-intensity resistance training on muscle changes in postmenopausal women with different angiotensin-converting enzyme insertion/deletion polymorphisms of interest. Menopause. 2019;26(8):899-905. doi:10.1097/GME.0000000000001364.

16.He L, Van Roie E, Bogaerts A, et al. Genetic predisposition score predicts the increases of knee strength and muscle mass after one-year exercise in healthy elderly. Exp Gerontol. 2018;111:17-26. doi:10.1016/j.exger.2018.06.030.

17.Zhao L, He LX, Huang SN, et al. Protection of Dopamine Neurons by Vibration Training and Up-Regulation of Brain-Derived Neurotrophic Factor in a MPTP Mouse Model of Parkinson’s Disease. Physiol Res. October 2014:649-657. doi:10.33549/physiolres.932743.